Metabolic Syndrome: Causes, Symptoms, and Treatment

Published in : Endocrinology and diabetology | May 13, 2025 |

Metabolic Syndrome: What It Is, Causes, Symptoms, and Treatment

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The World Health Organization (WHO) defines metabolic syndrome as a cluster of conditions, including abdominal obesity, insulin resistance, high blood pressure, and abnormal cholesterol or triglyceride levels. While different medical organisations offer different definitions, they all agree on the core components and the serious risks involved.

With the decline of infectious diseases due to better healthcare, non-communicable diseases (NCDs) like Metabolic Syndrome (MetS) have emerged as leading threats to public health. What began in the Western world is now a global epidemic driven by two powerful lifestyle changes: high-calorie, low-fibre diets and reduced physical activity. Moreover, sedentary lifestyle habits, fast food, and mechanised living—especially in urban areas of developing countries, have increased the prevalence of metabolic syndrome. India is no exception. Studies show that nearly one in four Indian adults may have metabolic syndrome.

Given its rising numbers and silent progression, metabolic syndrome calls for urgent awareness, early screening, and lifestyle intervention. In this blog, we will walk you through the causes, symptoms, diagnostic tests, and the best treatment options available for metabolic syndrome, so you can stay a step ahead of this modern health challenge.

What Is Metabolic Syndrome?

Metabolic syndrome is a cluster of conditions that increase the risk of developing cardiovascular disease, type 2 diabetes, and stroke. People diagnosed with metabolic syndrome have three out of five of these conditions or all:

  • Abdominal Obesity: A large waist circumference (over 40 inches for men and over 35 inches for women).
  • High Blood Pressure: Blood pressure of 130/85 mmHg or higher.
  • High Blood Sugar: Fasting glucose levels of 100 mg/dl or higher.
  • High Triglycerides: Triglyceride levels of 150 mg/dl or higher.
  • Low HDL Cholesterol: HDL cholesterol levels below 40 mg/dl for men and below 50 mg/dl for women.

Metabolic Syndrome Causes

The main underlying cause of metabolic syndrome is insulin resistance, which occurs when the body doesn’t use insulin properly. This leads to higher blood glucose levels and insulin levels, triggering other issues like weight gain and inflammation.

Common causes of insulin resistance are:

  • Obesity, especially fat around the abdomen
  • Lack of physical activity
  • Unhealthy diet (junk food, food items high in sugar and saturated fats)
  • Genetics
  • Hormonal imbalances
  • Smoking or alcohol use
  • Pre-existing conditions such as PCOS or fatty liver diseases

Our specialists at the SPARSH Hospital in Bangalore emphasise that early lifestyle changes can greatly reduce your risk of metabolic syndrome and its complications.

Metabolic Syndrome Symptoms

Metabolic syndrome often develops silently, with no noticeable symptoms. However, some signs may include:

  • Increased waistline
  • Frequent fatigue
  • Dark patches of skin (especially around the neck or armpits, medically referred to as acanthosis nigricans)
  • Frequent urination or thirst
  • Elevated blood pressure
  • Breathing issues like snoring or sleep apnea

At first, these metabolic syndrome symptoms may seem minor, but they can be important indicators of serious conditions like cardiovascular diseases, type 2 diabetes, and stroke. That’s why regular health checkups at an Endocrinology and Diabetology Hospital in Bangalore or another city are essential.

Metabolic Syndrome Test and Diagnosis

A metabolic syndrome test includes a combination of physical exams and lab tests to assess the five main risk factors:

  • Waist circumference
  • Blood pressure check
  • Fasting blood sugar test to check if the patient has diabetes
  • Lipid profile to measure triglycerides and HDL cholesterol
  • HbA1c levels to determine long-term glucose control level

Your doctor may also check liver enzymes, uric acid, or conduct ECG/ECHO to rule out early signs of cardiovascular disease.

Metabolic Syndrome Treatment

Treating metabolic syndrome involves tackling each risk factor. There’s no one-size-fits-all treatment procedure, but a combination of lifestyle changes and medication can be very effective.

1. Lifestyle Changes

The first line of defence is to focus on a healthy diet, physical exercise, and lifestyle changes. Here’s what you can do:

  • Focus on high-fiber foods, fruits, vegetables, whole grains, lean proteins, and healthy fats
  • Aim for at least 30 minutes of physical activity 5 days a week
  • Losing 5 to 10% of your body weight can improve insulin sensitivity
  • Ensure 7 to 8 hours of sleep to maintain metabolic balance
  • Quit smoking and reduce alcohol intake

2. Medicine for Metabolic Syndrome

When lifestyle changes aren’t enough, your doctor may prescribe to:

  • Control blood pressure
  • Manage cholesterol and triglycerides
  • Improve insulin sensitivity and lower blood glucose

Medication plans are always individualised, so consult a qualified diabetologist or endocrinologist before starting any medications.

How to Prevent Metabolic Syndrome?

Preventing metabolic syndrome begins with awareness and proactive health management. Here’s how you can reduce your risk:

  • Track your waistline and BMI regularly
  • Go for annual health checkups after the age of 30
  • Choose home-cooked meals over processed or fast foods
  • Move more: take the stairs, go for walks, stretch during work breaks
  • Manage stress with yoga, meditation, or counselling

When to See a Specialist?

If you have been diagnosed with prediabetes, high blood pressure, abnormal cholesterol, or if obesity runs in your family, consult a diabetologist or endocrinologist. Early detection and personalised care can prevent long-term complications.

We have a dedicated endocrinology and diabetology department at SPARSH, which offers state-of-the-art facilities for testing, diagnosis, and management of all metabolic diseases. Our team of the best endocrinologists and diabetologists in Bangalore is committed to helping you regain control over your health.

Conclusion

Metabolic syndrome is your body’s early warning system. If left unchecked, it can lead to life-altering conditions like heart disease, stroke, or type 2 diabetes. The good news is that it’s both preventable and manageable. You can reverse the course of this condition through early diagnosis, lifestyle adjustments, and medical care.

Frequently Asked Questions

Can metabolic disease be reversed? 

Yes, with lifestyle changes and medical support, metabolic syndrome can often be managed or reversed. 

Which exercises help manage metabolic disease? 

Aerobic activities like brisk walking, cycling, swimming, or dancing support heart health and help manage metabolic syndrome. 

How can insulin resistance be improved quickly? 

Healthy eating and regular physical activity are the two key points to improving insulin sensitivity over time. 

What kind of diet supports metabolic syndrome management? 

Diets rich in fruits, vegetables, whole grains, and healthy fats are commonly recommended. 

How can I check my metabolism? 

You can estimate your metabolism using online BMR or RMR calculators and blood tests. You can also consult your family doctor or a specialist for a full assessment. 

If you are concerned about your risk or looking for expert guidance, contact our specialists today! 


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