Dr. Smitha Shekar

Haematological disorders both benign and malignant conditions, malignant brain tumours, solid malignancies Ewings and osteosarcomas, and bone marrow transplant.

• Received multiple certifications both nationally and internationally.
• Attended training sessions to upgrade my skills to meet current standards.

Problem solving for better health – sponsored by DREYFUS HEALTH FOUNDATION, NEW YORK, USA

• New strategies in bone marrow transplant
• Brain tumors
• Cart cell therapy and advanced clinical research

• Prophylactic Granulocyte transfusions in patients post high dose chemotherapy/ hematopoietic stem cell transplant.
• Stroke in Sickle Cell Disease (SCD): Disease in Text book Elsevier by Dr Smitha and Dr Intezar
• Genomic profiling of Pediatric Hematology and Oncology patients using NGS:Single center experience -PHOCON 2024
• A Retrospective Multicentric INPHOG Study (Inpog-WT-18-02): Patterns of Care and Survival of Wilms Tumors in Children in India
• Revealing GFI-1b mutation as a storm in child previously diagnosed
• with ITP : E poster to ISBMT May 2024
• Hidden DOCK8 mutation in a child with Hyper IgE syndrome: E poster to ISBMT May 2024
• RAS Associated Leukoproliferative Disorder (RALD) due to NRAS
• Mutation Progressing to Acute Myeloid Leukemia: E Poster to 5th Emirates Pediatric Hematology and Oncology conference Jan 2023
• AML with Good risk Cytogenetics t(8;21) having horrendous
• Course due to Associated Systemic Masto cytosis : E Poster to 5th Emirates Pediatric Hematology and Oncology conference Jan 2023
• Elderheim Chester disease in a case of Infantile Leukemia : Case Report
• Disseminated Candidiasis in a case of ALL : Case Report
• Pedicon : Participated in Bangalore Pedicon 2016PET (Pediatric Epilepsy Training) : Conducted by BPNA (British Pediatric Neurological Association)
• IAP: 54th Annual Conference, Basic Mechanical Ventilation in Pediatrics & Poster presentation on Parkes weber syndrome
• Respicon : Participated in Respicon 2017 at 3rd Asian Pediatric pulmonology Society Meeting
• OSCE : Conducted by Texila American University in association with KMC
• Karnataka Pedicon 2017 : Poster presentation of Prider Willi & EBV associated HLH syndrome
• Investigator Meeting : Attended meeting in Dubai for Pain management trial which involves Sativex as the study drug & various other meetings.
• ICH GCP training : Conducted for a Phase III trial from Wyeth Pharmaceutical Ltd and GW pharmaceuticals.
• •Co-Investigator in Recurrent Metastatic Colorectal Phase III trial which involves Photo Dynamic therapy along with regular Chemotherapy.
• Phase I/II Trial for the investigational Targeted drug along with Herceptin in Newly diagnosed Metastatic Breast Cancer- INCYTE Global /Siroclinpharm®
• Phase II trial with investigational agent along with Paclitaxel and carboplatin in LABC/ Metastatic Breast cancer- PEREGRINE Co ®
• Phase III trial in Relapsed and Refractory Non-Hodgkin’s Lymphoma with Rituximab and anti CD 22 MAB compared to investigator choice of Chemo agent – Wyeth®
• Phase III trial in Metastatic RCC with Temsirolimus and Bevacizumab- Wyeth®, experience in e CRF.
• Cancer Pain study
• Capecitabine Bioequivalence Study, MBC and CRC
• CDX-110-04 An international randomized double blind controlled study of GM-CSF with adjuvant temozolomide in patients with newly diagnosed surgically resected EGFRV3 positive Glioblastoma Act-IV study
• A Randomized open label phase II study to assess the efficacy & safety of AZD4547 monotherapy VS Paclitaxel in patients with advanced Gastric adenocarcinoma (including lower 1/3rd of esophagus/GE Junction) with FGFR2 Polysomy or Gene amplication (Shine Study)

Indian Pediatric Hematology Oncology Group (PHO- IAP)