Interstitial Lung Disease (ILD) – Symptoms, Causes & Treatment

Published in : Pulmonology | November 22, 2025 |

Interstitial Lung Disease – Symptoms and Causes

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Interstitial lung disease (ILD) is a broad term that describes a group of disorders that cause progressive scarring (fibrosis) of the lungs. This scarring makes it difficult for oxygen to pass into the bloodstream, leading to breathing difficulties, fatigue, and reduced lung capacity. The condition affects the lung’s interstitium—the tissue and space around the air sacs (alveoli). Over time, the damage may become irreversible, making early diagnosis and ILD treatment essential for improving quality of life and slowing progression.

At SPARSH Hospitals, recognised as one of the best pulmonology hospitals in Bangalore, expert pulmonologists provide comprehensive care for ILD, offering advanced diagnostic tools and tailored ILD therapy to help patients breathe easier.

Understanding Interstitial Lung Disease

Interstitial lung disease refers to more than 200 different lung conditions that cause inflammation and scarring in the lung interstitium. This scarring thickens the tissue, reducing its ability to expand and take in oxygen.

Some common forms include:

  • Idiopathic Pulmonary Fibrosis (IPF): Scarring with no known cause.
  • Interstitial Pneumonia: Inflammation of the lung interstitium, often associated with infections or autoimmune conditions.
  • ILD with Rheumatoid Arthritis: Autoimmune diseases such as rheumatoid arthritis can trigger chronic lung inflammation.
  • Occupational ILD: Caused by long-term exposure to harmful dust, chemicals, or asbestos.

Regardless of the type, ILD reduces lung elasticity and makes breathing increasingly difficult.

Symptoms of ILD

Interstitial lung disease symptoms often develop gradually but can worsen quickly in some cases. The most common signs include:

  • Shortness of breath: Initially during exertion, later even at rest.
  • Dry, persistent cough: Typically non-productive and worsening over time.
  • Fatigue and weakness: Due to reduced oxygen supply.
  • Unexplained weight loss: Common in advanced stages of ILD.
  • Chest discomfort: Tightness or pain when breathing deeply.
  • Clubbing of fingers: Enlargement of fingertips due to chronic low oxygen.

In advanced stages of ILD, patients may experience severe breathing difficulty, frequent respiratory infections, and complications like pleural effusion (fluid around the lungs).

Causes of ILD

ILD Causes

There is no single cause of ILD; instead, multiple risk factors contribute:

  • Autoimmune diseases: Conditions like rheumatoid arthritis, scleroderma, and lupus.
  • Infections: Chronic lung infections, including tuberculosis, can trigger interstitial damage.
  • Occupational exposure: Long-term inhalation of asbestos, coal dust, or silica.
  • Medications: Certain chemotherapy or heart medications can damage lung tissue.
  • Radiation therapy: Exposure to chest radiation can increase ILD risk.
  • Genetics: A family history of ILD may predispose individuals to the disease.

Identifying the underlying cause is vital for planning appropriate ILD treatment.

Stages of ILD

The progression of ILD is categorized into stages, which help pulmonologists determine the right ILD therapy:

  • Early Stage: Mild breathlessness, dry cough, and fatigue.
  • Moderate Stage: More pronounced symptoms, reduced exercise tolerance, and scarring visible on imaging.
  • Severe Stage: Constant breathlessness, reduced lung capacity, and oxygen dependence.
  • Advanced Stage: Extensive scarring, frequent hospitalizations, and significant quality-of-life impact.

Early detection and intervention can slow the disease, making timely consultation with the best pulmonologist in Bangalore essential.

Diagnosis of ILD

Accurate diagnosis requires a multidisciplinary approach. At SPARSH Hospitals, pulmonologists employ advanced tools such as:

  • Chest X-ray & HRCT (High-Resolution CT): Detect scarring and patterns of interstitial damage.
  • Pulmonary Function Tests (PFTs): Assess lung capacity and airflow.
  • Blood Tests: Identify autoimmune markers linked to rheumatoid arthritis and other diseases.
  • Bronchoscopy & Lung Biopsy: Collect tissue samples to confirm diagnosis.
  • Echocardiogram: Rule out pulmonary hypertension as a complication.

Treatment for Interstitial Lung Disease

ILD Treatment Approaches

While lung scarring from ILD cannot be reversed, ILD therapy focuses on slowing progression, managing symptoms, and improving quality of life. Treatment options include:

  • 1. Medications:
    • Corticosteroids & Immunosuppressants to reduce inflammation.
    • Antifibrotic drugs to slow lung scarring in conditions like idiopathic pulmonary fibrosis.
  • Oxygen Therapy: Helps relieve shortness of breath and maintain adequate oxygen levels.
  • Pulmonary Rehabilitation: Exercise, breathing exercises, and nutrition counseling to build lung strength.
  • Treatment of Underlying Conditions: Managing autoimmune diseases like rheumatoid arthritis or infections like tuberculosis.
  • Lung Transplant: In advanced cases, a transplant may be considered.

At SPARSH, the best pulmonologist in Bangalore designs personalized treatment plans to address each patient’s unique needs.

Complications of ILD

If left untreated, ILD can lead to serious health issues:

  • Pulmonary Hypertension: High blood pressure in the lungs.
  • Pleural Effusion: Fluid buildup around the lungs, making breathing harder.
  • Respiratory Failure: Inability of the lungs to supply sufficient oxygen.
  • Increased Infection Risk: Due to weakened lung function.

Prevention and Lifestyle Management

While some ILD causes cannot be avoided, preventive steps and lifestyle changes can help:

  • Avoid exposure: Stay away from dust, fumes, and harmful chemicals.
  • Quit smoking: Smoking worsens lung scarring and accelerates disease.
  • Manage autoimmune conditions: Early control of rheumatoid arthritis and related diseases.
  • Vaccinations: Protect against influenza and pneumonia.
  • Regular check-ups: Early detection ensures better management.

When to See a Doctor

Consult a pulmonologist if you experience:

  • Persistent dry cough lasting more than a few weeks.
  • Shortness of breath that worsens with activity.
  • Chest pain, fatigue, or unexplained weight loss.
  • History of autoimmune disease or long-term occupational exposure.

For those experiencing severe or prolonged symptoms, visiting a trusted center like SPARSH Hospitals, renowned as the best pulmonology hospital in Bangalore, ensures timely diagnosis and specialized ILD therapy.

Conclusion

Interstitial lung disease is a chronic and progressive condition that requires early recognition and comprehensive management. From autoimmune triggers like rheumatoid arthritis to infections such as tuberculosis, the causes are diverse, but the outcomes can be managed with prompt and expert care.

At SPARSH Hospitals, home to the best pulmonologists in Bangalore, patients receive world-class diagnosis, treatment, and rehabilitation support. With advanced therapies and patient-focused care, ILD can be managed effectively, helping individuals breathe better and live fuller lives.

Frequently Asked Questions

What is interstitial lung disease

It is a group of lung disorders that cause scarring of lung tissue, making it harder to breathe and absorb oxygen.

What are the main causes of ILD

ILD causes include autoimmune conditions like rheumatoid arthritis, infections such as tuberculosis, occupational exposures, certain medications, and genetic predisposition.

Can ILD be cured

While scarring from ILD cannot be reversed, ILD treatment can slow disease progression, reduce symptoms, and improve quality of life.

What are the stages of ILD

The stages of ILD range from early symptoms like mild cough and breathlessness to advanced stages requiring oxygen therapy or a lung transplant.

Who should I consult for ILD treatment in Bangalore

Consult the best pulmonologist in Bangalore at SPARSH Hospitals, known for advanced diagnostics, personalized care, and being the best pulmonology hospital in Bangalore.


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